1. Elastoderma

Your body may produce too much elastin, a protein that gives skin strength and flexibility, in specific areas. When stretched, your skin does not spring back, and it sags and folds. It’s unclear why this occurs. It commonly manifests as in the neck, arms, or legs, particularly around the elbows and knees. The loose skin may be taken removed by your doctor, but the condition usually reappears.

2. Acanthosis Nigricans

You could try scrubbing these dark, thick, velvety patches of skin off, especially if they itch and stink. But it’s not going to work. Elbows, knees, knuckles, and armpits are common locations. Although the disease is harmless, it might be a symptom of other issues such as obesity, diabetes, hormone issues, a drug reaction, or even cancer. Consult your physician.

3. Xeroderma Pigmentosum

Inherited genes prevent your body from repairing cells that have been harmed by ultraviolet (UV) radiation, such as those emitted by lightbulbs. This increases your risk of skin cancer by 10,000 times, and most people with XP develop it by the age of ten. Freckles appear before the age of two, as do black patches, a severe sunburn, and extremely dry skin following exposure to the sun. You must cover every inch of skin (with sunscreen below) and use UV-blocking goggles to be safe.

4. Argyria

The bluish-gray tint of your skin is caused by small silver particles that accumulate in your tissues. Colloidal silver, a dietary supplement that some individuals take, can cause it, and it’s typically permanent. It’s possible that the sun will aggravate the situation. Colloidal silver has no proven health advantages, and it may impede the absorption of medications like thyroxine and antibiotics.

5. Blau Syndrome

It usually begins as a scaly rash on your trunk, arms, or legs before the age of four, with hard bumps under your skin. Your immune system overreacts with excessive inflammation as a result of this hereditary condition. A lot of people who have it also have arthritis and vision issues, and some of them develop kidney illness. You may have a kind of sarcoidosis called early-onset sarcoidosis if neither of your parents have it.

6. Leprosy

People who aren’t naturally immune (which is most of us) could contract it from another person or from handling an armadillo. It can take years for symptoms to appear. Look for a rash or reddish spots on the skin, as well as swollen skin and numbness in that area or a finger or toe. Your eyes may become extremely light-sensitive. Antibiotics normally heal it, and if you don’t wait too long to treat it, you should be ok.

7. Fish Scale Disease

Dry skin, a flaky scalp, little fish-like scales (particularly on your elbows and lower thighs), and deep, painful cracks result from a keratin buildup caused by a lag in your skin’s regular shedding. It’s possible that your skin will darken as well. Ichthyosis vulgaris can be inherited from a parent may be linked to a medical condition such as cancer, thyroid disease, or HIV/AIDS. It tends to become better if you live somewhere hot and humid.

8. Eruptive Xanthomas

When these uneven, wart-like, waxy pimples appear on your skin, it can be worrying, but they’re not an infection, and they’re not contagious. They’re cholesterol fatty deposits created by high amounts of triglycerides, a form of fat in the blood. The lumps will normally go away when you start taking medicine and changing your diet for a few weeks.

9. Primary Cutaneous Amyloidosis

An aberrant protein called amyloid that grows up in your skin is linked to this group of diseases. The most common sites for lichen amyloidosis are the shins, thighs, feet, and forearms. It looks like reddish-brown elevated patches and is irritating. Macular amyloidosis appears as flat, dusty-colored spots between your shoulder blades or on your chest. Nodular amyloidosis can cause firm, reddish pimples on your body and face that don’t itch.

10. Erythropoietic Protoporphyria

People with this condition have alterations (mutations) in their genes that make it difficult for their bodies to metabolize protoporphyrin, a light-sensitive molecule. It accumulates in the skin’s top layers and reacts to light from the sun and other sources. It’s possible that your skin will tingle, itch, or burn. It may blister and hurt if you don’t cover it up. Drugs, a kind of vitamin A, and iron may be of assistance.

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